Hyperlactatemia and Human Immunodeficiency Virus Infection: Lessons from the Era of Antiretroviral Monotherapy

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Hyperlactatemia and human immunodeficiency virus infection: lessons from the era of antiretroviral monotherapy.

Lactic acidosis is a life-threatening complication of antiretroviral therapy with nucleoside reverse transcriptase inhibitors (NRTIs) (2, 3), and there is a spectrum of conditions associated with lactic acid elevation, ranging from moderate asymptomatic hyperlactatemia to life-threatening lactic acidosis. Identification of the compounds responsible for hyperlactatemia is uneasy, because most pa...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2002

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.46.11.3683.2002